Genetic diversity of multidrug-resistant Mycobacterium tuberculosis isolates and identification of 11 novel rpoB alleles in Taiwan.

نویسندگان

  • Ruwen Jou
  • Huang-Yau Chen
  • Chen-Yuan Chiang
  • Ming-Chih Yu
  • Ih-Jen Su
چکیده

Of 162 multidrug-resistant Mycobacterium tuberculosis isolates from Taiwan, 60.5% were found to belong to the Beijing family on the basis of spoligotyping results. IS6110 restriction fragment length polymorphism fingerprinting showed genetic diversity among the multidrug-resistant isolates. Furthermore, 90.1% of the multidrug-resistant isolates had mutations in the rpoB gene, and 11 novel alleles were recognized.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 43 3  شماره 

صفحات  -

تاریخ انتشار 2005